2024
Luo Z, Wan Z, Ren P, Zhang B, et al. In Situ Formation of Fibronectin-Enriched Protein Corona on Epigenetic Nanocarrier for Enhanced Synthetic Lethal Therapy. Adv Sci (Weinh). 2024:e2307940. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/38482976/
West RE 3rd, Oberly PJ, Riddler SA, Nolin TD, Devanathan AS. Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method to quantify antiretroviral drug concentrations in human plasma for therapeutic monitoring. J Pharm Biomed Anal. 2024;240:115932. https://pubmed.ncbi.nlm.nih.gov/38198884/
2023
Chen E, Shaffer MG, Bilodeau RE, West RE, Oberly PJ, Nolin TD, Culyba MJ. Clinical Rel mutations in Staphylococcus aureus primes pathogen expansion under nutrient stress. eSphere 2023;8(5):e0024923. https://pubmed.ncbi.nlm.nih.gov/37750686/
West RE 3rd, Oberly PJ, Riddler SA, Nolin TD, Devanathan AS. Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for quantifying lenacapavir plasma concentrations: Application to therapeutic monitoring. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Oct 15:1230:123905. https://pubmed.ncbi.nlm.nih.gov/37866010/
Yoshida S, Kreger AM, Shaik IH, West RE 3rd, Venkataramanan R, Gittes GK. Intra-amniotic sildenafil administration in rabbits: Safety, pharmacokinetics, organ distribution and histologic evaluation. Toxicol Appl Pharmacol. 2023;469:116527. https://pubmed.ncbi.nlm.nih.gov/37080362/
Zhang Y, Li J, Huang Y, Chen Y, Luo Z, et al. Improved antitumor activity against prostate cancer via synergistic targeting of Myc and GFAT-1. Theranostics. 2023;13(2):578-595. https://pubmed.ncbi.nlm.nih.gov/36632215/
Wan Z, Huang H, West RE 3rd, Zhang M, Zhang B, et al. Overcoming pancreatic cancer immune resistance by codelivery of CCR2 antagonist using a STING-activating gemcitabine-based nanocarrier. Materials Today. 2023;62:33-50. https://doi.org/10.1016/j.mattod.2022.11.008
Thurston RC, Wu M, Chang Y, Aizenstein HJ, Derby CA, Barinas-Mitchell EA, Maki P. Menopausal Vasomotor Symptoms and White Matter Hyperintensities in Midlife Women. Neurology. 2023;100(2):e133-e141. https://pubmed.ncbi.nlm.nih.gov/36224031/
2022
Baumgartner NE, McQuillen SM, Perry SF, Miller S, Maroteaux MJ, et al. History of Previous Midlife Estradiol Treatment Permanently Alters Interactions of Brain Insulin-like Growth Factor-1 Signaling and Hippocampal Estrogen Synthesis to Enhance Cognitive Aging in a Rat Model of Menopause. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022;42(42):7969-7983. https://pubmed.ncbi.nlm.nih.gov/36261268/
Lefever DE, Miedel MT, Pei F, DiStefano JK, Debiasio R, et al. A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies. Metabolites. 2022;12(6):528. https://pubmed.ncbi.nlm.nih.gov/35736460/
Thurston RC, Jakubowski KP, Wu M, Aizenstein HJ, Chang Y, Derby CA, Koenen KC, Barinas-Mitchell E, Maki PM. Brain Imaging Behav. Sexual assault and white matter hyperintensities among midlife women 2022;16(2):773-780. https://pubmed.ncbi.nlm.nih.gov/34553332/
Jackson EK, Kitsios GD, Lu MY, Schaefer CM, Kessinger CJ, et al. Suppressed renoprotective purines in COVID-19 patients with acute kidney injury. Scientific reports. 2022;12(1):17353. https://pubmed.ncbi.nlm.nih.gov/36253495/
Birabaharan J, West RE 3rd, Nolin TD, Traube C, Bell MJ, Empey PE. Simultaneous detection of a panel of nine sedatives and metabolites in plasma from critically ill pediatric patients via UPLC-MS/MS. J Pharm Biomed Anal. 2022;218:114853. https://pubmed.ncbi.nlm.nih.gov/35659658/
Sawyer CW, Tuey SM, West RE 3rd, Nolin TD, Joy MS. Physiologically based pharmacokinetic modeling of vitamin D3 and metabolites in vitamin D insufficient patients. Drug Metab Dispos. 2022 Jul 2:DMD-AR-2021-000609. doi: 10.1124/dmd.121.000609. Epub ahead of print. PMID: 35779863. https://pubmed.ncbi.nlm.nih.gov/35779863/
2021
West RE, Oberly P, Wen J, Nolin TD. Development of a robust UPLC–MS/MS method for the simultaneous quantification of sildenafil and N-desmethyl sildenafil in multiple biological matrices. Presented at ASMS 2021, the 69th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Philadelphia, PA, November 2021. Full poster presentation
Thurston RC, Fritz MM, Chang Y, Barinas-Mitchell E, Maki PM. Self-compassion and subclinical cardiovascular disease among midlife women. Health Psychol. 2021;40(11):747-753. https://pubmed.ncbi.nlm.nih.gov/34914480/
Thurston RC, Jakubowski K, Chang Y, Koenen K, Maki PM, Barinas-Mitchell E. Sexual Assault and Carotid Plaque Among Midlife Women. J Am Heart Assoc.. 2021;10(5):e017629. https://pubmed.ncbi.nlm.nih.gov/33619993/
2020
Thurston RC, Wu M, Aizenstein HJ, Chang Y, Barinas-Mitchell E, Derby CA, Maki PM. Sleep characteristics and white matter hyperintensities among midlife women. Sleep. 2020;43(6):zsz298. https://pubmed.ncbi.nlm.nih.gov/31863110/
Cortés YI, Barinas-Mitchell E, Suder Egnot N, Bhasin S, Jasuja R, Santoro N, et al. Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women. J Clin Endocrinol Metab. 2020;105(4):1126-36. https://pubmed.ncbi.nlm.nih.gov/31900485/
Casal MA, Prebehalla L, West RE, Shah N, Chonchol M, Joy MS, Nolin TD. Effect of kidney disease and vitamin D repletion on drug transporter activity. Presented virtually at ASN Kidney Week 2020, the American Society of Nephrology Annual Meeting, originally scheduled for Denver, CO, October 2020. Full poster presentation
Jauhari A, Baranov SV, Suofu Y, Kim J, Singh T, Yablonska S, et al. Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration. J Clin Invest. 2020;130(6):3124-36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260019/
Silva-Barbosa AC, Zhou D, Xie Y, Choi Y, Tung H, et al. Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice. J Am Soc Nephrol. 2020;31(7):1496–1508. https://pubmed.ncbi.nlm.nih.gov/32424001/
West RE, Nolin TD. Development of a sensitive and high-throughput UPLC–MS/MS method for the quantification of 1-methylnicotinamide in human serum and urine. Presented virtually at ASMS 2020, the 68th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, originally scheduled for Houston, TX, June 2020. Full poster presentation
Casal MA, Prebehalla L, West RE, Shah N, Chonchol M, Joy MS, Nolin TD. Effect of kidney disease and vitamin D repletion on drug transporter activity. Presented virtually at ASN Kidney Week 2020, the American Society of Nephrology Annual Meeting, originally scheduled for Denver, CO, October 2020. Full poster presentation
Kimber C, Zhang S, Johnson C, West RE, Prokopienko AJ, Mahnken JD, et al. Randomized, Placebo-Controlled Trial of Rifaximin Therapy for Lowering Gut-Derived Cardiovascular Toxins and Inflammation in CKD. Kidney360. 2020;1(11):1206. https://kidney360.asnjournals.org/content/1/11/1206/
Jawale CV, Ramani K, Li DD, Coleman BM, Oberoi RS, Kupul S, Lin L, Desai JV, Delgoffe GM, Lionakis MS, Bender FH, Prokopienko AJ, Nolin TD, Gaffen SL, Biswas PS. Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease. Sci Transl Med. 2020;12(548):eaay5691. https://pubmed.ncbi.nlm.nih.gov/32554707/
2019
Zhang J, Tang C, Oberly PJ, Minnigh MB, Achilles SL, Poloyac SM. A sensitive and robust UPLC-MS/MS method for quantitation of estrogens and progestogens in human serum. Contraception. 2019;99(4):244-50. https://pubmed.ncbi.nlm.nih.gov/30685285/
West RE, Nolin TD. Development of a high-throughput UPLC–MS/MS method for the simultaneous determination of fexofenadine and olmesartan in human serum. Presented at ASMS 2019, the 67th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, June 2019. Full poster presentation
Osier ND, Ziari M, Puccio AM, Poloyac S, Okonkwo DO, Minnigh MB, et al. Elevated cerebrospinal fluid concentrations of N-acetylaspartate correlate with poor outcome in a pilot study of severe brain trauma. Brain Inj. 2019;33(10):1364-71. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675639/
Jackson TC, Kotermanski SE, Kochanek PM, Jackson EK. Oxidative stress induces release of 2'-AMP from microglia. Brain Res. 2019;1706:101-9. https://pubmed.ncbi.nlm.nih.gov/30395838/
Prokopienko AJ, West RE, Schrum DP, Stubbs JR, Leblond FA, Pichette V, et al. Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease. Sci Rep. 2019;9(1):15901. https://pubmed.ncbi.nlm.nih.gov/31685846/
Stubbs JR, Stedman MR, Liu S, Long J, Franchetti Y, West RE, 3rd, et al. Trimethylamine N-Oxide and Cardiovascular Outcomes in Patients with ESKD Receiving Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2019;14(2):261-7. https://pubmed.ncbi.nlm.nih.gov/30665924/
Prokopienko AJ, West RE, 3rd, Stubbs JR, Nolin TD. Development and validation of a UHPLC-MS/MS method for measurement of a gut-derived uremic toxin panel in human serum: An application in patients with kidney disease. J Pharm Biomed Anal. 2019;174:618-24. https://pubmed.ncbi.nlm.nih.gov/31276982/
2018
Miller TM, Poloyac SM, Anderson KB, Waddell BL, Messamore E, Yao JK. A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity. Prostaglandins Leukot Essent Fatty Acids. 2018;136:153-9. https://pubmed.ncbi.nlm.nih.gov/28111064/
Miller TM, Poloyac SM, Anderson KB, Waddell BL, Messamore E, Yao JK. A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity. Prostaglandins Leukot Essent Fatty Acids. 2018;136:153-9. https://pubmed.ncbi.nlm.nih.gov/28111064/
Thurston RC, Bhasin S, Chang Y, Barinas-Mitchell E, Matthews KA, Jasuja R, et al. Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women. J Clin Endocrinol Metab. 2018;103(8):3070-7. https://pubmed.ncbi.nlm.nih.gov/29788255/
Achilles SL, Mhlanga FG, Musara P, Poloyac SM, Chirenje ZM, Hillier SL. Misreporting of contraceptive hormone use in clinical research participants. Contraception. 2018;97(4):346-53. https://pubmed.ncbi.nlm.nih.gov/28966052/
Ramezani A, Nolin TD, Barrows IR, Serrano MG, Buck GA, Regunathan-Shenk R, et al. Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e-/- Mice. Sci Rep. 2018;8(1):14752-. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170401/
Johnson C, Prokopienko AJ, West RE, 3rd, Nolin TD, Stubbs JR. Decreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in Mice. Drug Metab Dispos. 2018;46(9):1304-9. https://pubmed.ncbi.nlm.nih.gov/29915157/
2017
Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, et al. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proc Natl Acad Sci U S A. 2017;114(38):E7997-e8006. https://pubmed.ncbi.nlm.nih.gov/28874589/
Keller AS, Diederich L, Panknin C, DeLalio LJ, Drake JC, Sherman R, et al. Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway. Am J Physiol Cell Physiol. 2017;313(6):C593-c603. https://pubmed.ncbi.nlm.nih.gov/28855161/
2016
Alshogran OY, Ocque AJ, Leblond FA, Pichette V, Nolin TD. Validation and Application of a Simple UHPLC-MS-MS Method for the Enantiospecific Determination of Warfarin in Human Urine. J Chromatogr Sci. 2016;54(4):554-60. https://pubmed.ncbi.nlm.nih.gov/26657732/
2015
Verrier JD, Kochanek PM, Jackson EK. Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP. J Pharmacol Exp Ther. 2015;354(2):175-83. https://pubmed.ncbi.nlm.nih.gov/25998049/
Ocque AJ, Stubbs JR, Nolin TD. Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine. J Pharm Biomed Anal. 2015;109:128-35. https://pubmed.ncbi.nlm.nih.gov/25767908/
Limdi NA, Nolin TD, Booth SL, Centi A, Marques MB, Crowley MR, et al. Influence of kidney function on risk of supratherapeutic international normalized ratio-related hemorrhage in warfarin users: a prospective cohort study. Am J Kidney Dis. 2015;65(5):701-9. https://pubmed.ncbi.nlm.nih.gov/25468385/
Alshogran OY, Naud J, Ocque AJ, Leblond FA, Pichette V, Nolin TD. Effect of experimental kidney disease on the functional expression of hepatic reductases. Drug Metab Dispos. 2015;43(1):100-6. https://pubmed.ncbi.nlm.nih.gov/25332430/
Alshogran OY, Urquhart BL, Nolin TD. Downregulation of Hepatic Carbonyl Reductase Type 1 in End-Stage Renal Disease. Drug Metab Lett. 2015;9(2):111-8. https://pubmed.ncbi.nlm.nih.gov/26282591/
2014
Shaik JS, Miller TM, Graham SH, Manole MD, Poloyac SM. Rapid and simultaneous quantitation of prostanoids by UPLC-MS/MS in rat brain. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;945-946:207-16. https://pubmed.ncbi.nlm.nih.gov/24355215/
Stubbs JR, Zhang S, Friedman PA, Nolin TD. Decreased conversion of 25-hydroxyvitamin D3 to 24,25-dihydroxyvitamin D3 following cholecalciferol therapy in patients with CKD. Clin J Am Soc Nephrol. 2014;9(11):1965-73. https://pubmed.ncbi.nlm.nih.gov/25183657/
Alshogran OY, Ocque AJ, Zhao J, Day BW, Leblond FA, Pichette V, et al. Determination of warfarin alcohols by ultra-high performance liquid chromatography-tandem mass spectrometry: application to in vitro enzyme kinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;944:63-8. https://pubmed.ncbi.nlm.nih.gov/24291722/
2013
Shaik JSB, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, et al. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. Am J Physiol Heart Circ Physiol. 2013;305(11):H1605-H13. https://pubmed.ncbi.nlm.nih.gov/24043255/
Thampatty BP, Klamerus MM, Oberly PJ, Feldman KL, Bell MJ, Tyler-Kabara EC, et al. Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury. Pediatr Crit Care Med. 2013;14(4):403-12. https://pubmed.ncbi.nlm.nih.gov/23439461/
2011
Gibbs RB, Chipman AM, Hammond R, Nelson D. Galanthamine plus estradiol treatment enhances cognitive performance in aged ovariectomized rats. Horm Behav. 2011;60(5):607-16. https://pubmed.ncbi.nlm.nih.gov/21889940/
2009
Miller TM, Donnelly MK, Crago EA, Roman DM, Sherwood PR, Horowitz MB, et al. Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(31):3991-4000. https://pubmed.ncbi.nlm.nih.gov/19892608/
Li J, Wilson A, Gao X, Kuruba R, Liu Y, Poloyac S, et al. Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. J Pharmacol Exp Ther. 2009;331(1):234-43. https://pubmed.ncbi.nlm.nih.gov/19605523/