The SMBC is a mass spectrometry resource of the Health Sciences Core Research Facilities (HSCRF) and Clinical and Translational Science Institute (CTSI). It was established in 2009, and partially funded by two NIH shared instrument grants (S10RR023461 and S10OD028540). We provide services for quantitative analysis of small molecules in biological samples using state-of-the-art ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS).

Our highly sensitive and specific UPLC-MS/MS methods allow users to obtain accurate quantitative measurements of multiple small molecules in a given sample, maximizing the ability to link basic science with preclinical and clinical outcomes. The robustness and reproducibility of our methods provide critical analytical support for successful execution of longitudinal studies. All questions related to the SMBC should be directed to Dr. Raymond E. West III.

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The SMBC provides accurate and absolute quantitation of various small molecules in biological samples. Our services include assay development and validation, and sample analysis with or without sample processing. New UPLC-MS/MS assays are constantly being developed and validated. Please contact Dr. Raymond E. West III for more information.

Images depict accurate and sensitive quantification via test vials, sample preparation, data collection, and data analysis and reporting.