Method Papers:
1. Miller TM, Donnelly MK, Crago EA, Roman DM, Sherwood PR, Horowitz MB, et al. Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. Journal of chromatography B, Analytical technologies in the biomedical and. 2009;877(31):3991-4000. https://pubmed.ncbi.nlm.nih.gov/19892608/
2. Miller TM, Poloyac SM, Anderson KB, Waddell BL, Messamore E, Yao JK. A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity. Prostaglandins Leukot Essent Fatty Acids. 2018;136:153-9. https://pubmed.ncbi.nlm.nih.gov/28111064/
Application Papers:
3. Donnelly MK, Crago EA, Conley YP, Balzer JR, Ren D, Ducruet AF, et al. 20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients. J Cereb Blood Flow Metab. 2015;35(9):1515-22. https://pubmed.ncbi.nlm.nih.gov/25920956/
4. Tyurina YY, Poloyac SM, Tyurin VA, Kapralov AA, Jiang J, Anthonymuthu TS, et al. A mitochondrial pathway for biosynthesis of lipid mediators. Nat Chem. 2014;6(6):542-52. https://pubmed.ncbi.nlm.nih.gov/24848241/
5. Schuck RN, Zha W, Edin ML, Gruzdev A, Vendrov KC, Miller TM, et al. The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease. PLoS One. 2014;9(10):e110162. https://pubmed.ncbi.nlm.nih.gov/25310404/
6. Shaik JSB, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, et al. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. Am J Physiol Heart Circ Physiol. 2013;305(11):H1605-H13. https://pubmed.ncbi.nlm.nih.gov/24043255/
7. Theken KN, Deng Y, Schuck RN, Oni-Orisan A, Miller TM, Kannon MA, et al. Enalapril reverses high-fat diet-induced alterations in cytochrome P450-mediated eicosanoid metabolism. Am J Physiol Endocrinol Metab. 2012;302(5):E500-E9. https://pubmed.ncbi.nlm.nih.gov/22185841/
8. Theken KN, Deng Y, Kannon MA, Miller TM, Poloyac SM, Lee CR. Activation of the acute inflammatory response alters cytochrome P450 expression and eicosanoid metabolism. Drug Metab Dispos. 2011;39(1):22-9. https://pubmed.ncbi.nlm.nih.gov/20947618/
9. Nayeem MA, Poloyac SM, Falck JR, Zeldin DC, Ledent C, Ponnoth DS, et al. Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice. Am J Physiol Heart Circ Physiol. 2008;295(5):H2068-H78. https://pubmed.ncbi.nlm.nih.gov/18805895/
10. Mu Y, Klamerus MM, Miller TM, Rohan LC, Graham SH, Poloyac SM. Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation. Drug Metab Dispos. 2008;36(11):2324-30. https://pubmed.ncbi.nlm.nih.gov/18725506/